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Symbol
Name
ID
Runx3
runt related transcription factor 3
MGI:102672
Phenotype annotations related to digestive/alimentary system
Darker colors indicate more annotations
Human Phenotypes
Colon cancer
Intestinal pseudo-obstruction
Intermittent diarrhea
Nausea and vomiting
Functional intestinal obstruction
Neoplasm of the liver
Disease(s) Associated with RUNX3
pancreatic cancer

Mouse Phenotypes
abnormal crypts of Lieberkuhn morphology
abnormal large intestine morphology
abnormal cecum morphology
abnormal colon morphology
abnormal stomach mucosa morphology
abnormal gastric chief cell morphology
abnormal gastric parietal cell morphology
abnormal stomach epithelium morphology
stomach mucosa hyperplasia
increased stomach mucosa thickness
abnormal digestive system physiology
intestinal inflammation
colitis
small intestinal inflammation
stomach inflammation
Availability Mouse Genotype
Runx3tm1Yg/Runx3tm1Yg
Runx3tm1Yito/Runx3tm1Yito
Runx3tm3.1Yg/Runx3tm3.1Yg

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory